The most commonly sought medical attention is for joint pain, with the small joints of the hand and wrist usually affected, although all joints are at risk. Discoid lupus can affect the blood vessels in the skin. The blood vessels themselves can become inflamed. This is known as vasculitis. Vasculitis can cause painful red spots frequently on the hands and feat and sometimes chilblain type rashes.
Drug-induced lupus erythematosus is a (generally) reversible condition that usually occurs in people being treated for a long-term illness. Drug-induced lupus mimics SLE. However, symptoms of drug-induced lupus generally disappear once the medication that triggered the episode is stopped. More than 38 medications can cause this condition, the most common of which are procainamide, isoniazid, hydralazine, quinidine, and phenytoin.